P198S (p.Pro198Ser) variant of POGZ (Q7Z3K3)
P198S (p.Pro198Ser) in POGZ (Q7Z3K3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data and structural context.
P198S (p.Pro198Ser) variant details
- p.Pro198Ser
- gnomAD rs1329204977
- Missense
- Variant Prioritization Score for Impact Estimate 0.488
- REVEL 0.38
- ESM-1b 0.00
- AlphaMissense 0.53
- CADD 25.30
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available