P191T (p.Pro191Thr) variant of POGZ (Q7Z3K3)
P191T (p.Pro191Thr) in POGZ (Q7Z3K3) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes structural context.
P191T (p.Pro191Thr) variant details
- p.Pro191Thr
- rs1199579958
- NCI-TCGA Cosmic COSV9965
- cosmic curated COSV99652
- gnomAD rs1199579958
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- ESM-1b 0.00
- AlphaMissense 0.50
- MetaLR 0.02
- MetaSVM -0.95
- PolyPhen-2 1.00
- SIFT 0.01
- UniProt: Variant assessed as somatic; moderate impact.
- Structural context available