N159D (p.Asn159Asp) variant of POGZ (Q7Z3K3)
N159D (p.Asn159Asp) in POGZ (Q7Z3K3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
N159D (p.Asn159Asp) variant details
- p.Asn159Asp
- ExAC rs752445050
- gnomAD rs752445050
- Missense
- Variant Prioritization Score for Impact Estimate 0.424
- REVEL 0.14
- ESM-1b 0.88
- AlphaMissense 0.84
- CADD 26.90
- PolyPhen-2 0.97
- SIFT 0.04
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available