K84T (p.Lys84Thr) variant of POGZ (Q7Z3K3)
K84T (p.Lys84Thr) in POGZ (Q7Z3K3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
K84T (p.Lys84Thr) variant details
- p.Lys84Thr
- ExAC rs756360462
- gnomAD rs756360462
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.21
- ESM-1b 0.00
- AlphaMissense 0.68
- CADD 22.40
- PolyPhen-2 0.01
- SIFT 0.12
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available