G154R (p.Gly154Arg) variant of POGZ (Q7Z3K3)
G154R (p.Gly154Arg) in POGZ (Q7Z3K3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and structural context.
G154R (p.Gly154Arg) variant details
- p.Gly154Arg
- TOPMed rs1658381566
- gnomAD rs1658381566
- Missense
- Variant Prioritization Score for Impact Estimate 0.55
- REVEL 0.35
- ESM-1b 0.40
- AlphaMissense 1.00
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available