p.Gln34 Pro35insAlaSer variant of PML (Protein PML)

Name: PML p.Gln34 Pro35insAlaSer variant | CATVariant
Creator: Center for Precision Medicine and Data Sciences
Published: 2026-08-21
License: https://catvariant.com/terms-of-use

p.Gln34 Pro35insAlaSer in PML (Protein PML) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.

p.Gln34 Pro35insAlaSer variant details

gnomAD 15-73994914-G-GGC
Inframe Insertion
Variant Prioritization Score for Impact Estimate 0.406
CADD 10.90
Most common in the East Asian population (allele frequency 2.8e-05)
Structural context available
Literature evidence available