T28S (p.Thr28Ser) variant of PML (Protein PML)
T28S (p.Thr28Ser) in PML (Protein PML) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data, published literature, and structural context.
T28S (p.Thr28Ser) variant details
- p.Thr28Ser
- gnomAD 15-73994894-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.054
- REVEL 0.04
- CADD 0.01
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available
- Literature evidence available