R7* (p.Arg7Ter) variant of PML (Protein PML)
R7* (p.Arg7Ter) in PML (Protein PML) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
R7* (p.Arg7Ter) variant details
- p.Arg7Ter
- NCI-TCGA TCGA novel
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.243
- CADD 22.90
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Non-Finnish European population (allele frequency 9.2e-07)
- Structural context available