R10M (p.Arg10Met) variant of PML (Protein PML)
R10M (p.Arg10Met) in PML (Protein PML) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
R10M (p.Arg10Met) variant details
- p.Arg10Met
- gnomAD rs1168158486
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.05
- CADD 15.00
- PolyPhen-2 0.08
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available