P25S (p.Pro25Ser) variant of PML (Protein PML)
P25S (p.Pro25Ser) in PML (Protein PML) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
P25S (p.Pro25Ser) variant details
- p.Pro25Ser
- gnomAD 15-73994885-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.03
- CADD 11.90
- PolyPhen-2 0.01
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available
- Literature evidence available