P25A (p.Pro25Ala) variant of PML (Protein PML)
P25A (p.Pro25Ala) in PML (Protein PML) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
P25A (p.Pro25Ala) variant details
- p.Pro25Ala
- gnomAD 15-73994885-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.207
- REVEL 0.04
- CADD 14.60
- PolyPhen-2 0.04
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.9e-06)
- Structural context available
- Literature evidence available