P24S (p.Pro24Ser) variant of PML (Protein PML)
P24S (p.Pro24Ser) in PML (Protein PML) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
P24S (p.Pro24Ser) variant details
- p.Pro24Ser
- TOPMed rs1274872826
- gnomAD rs1274872826
- Missense
- Variant Prioritization Score for Impact Estimate 0.162
- REVEL 0.06
- CADD 15.20
- PolyPhen-2 0.27
- SIFT 0.09
- Most common in the South Asian population (allele frequency 0.00021)
- Structural context available