P21S (p.Pro21Ser) variant of PML (Protein PML)
P21S (p.Pro21Ser) in PML (Protein PML) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
P21S (p.Pro21Ser) variant details
- p.Pro21Ser
- gnomAD rs1466002928
- Missense
- Variant Prioritization Score for Impact Estimate 0.11
- REVEL 0.02
- CADD 12.60
- PolyPhen-2 0.03
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 9.3e-07)
- Structural context available