P21R (p.Pro21Arg) variant of PML (Protein PML)
P21R (p.Pro21Arg) in PML (Protein PML) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
P21R (p.Pro21Arg) variant details
- p.Pro21Arg
- TOPMed rs2069392568
- Missense
- Variant Prioritization Score for Impact Estimate 0.264
- REVEL 0.09
- CADD 22.90
- PolyPhen-2 0.71
- SIFT 0.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available