P15L (p.Pro15Leu) variant of PML (Protein PML)
P15L (p.Pro15Leu) in PML (Protein PML) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
P15L (p.Pro15Leu) variant details
- p.Pro15Leu
- gnomAD 15-73994856-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.142
- REVEL 0.04
- CADD 12.10
- PolyPhen-2 0.02
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available