L31I (p.Leu31Ile) variant of PLN (Phospholamban)
L31I (p.Leu31Ile) in PLN (Phospholamban) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
L31I (p.Leu31Ile) variant details
- p.Leu31Ile
- NCI-TCGA TCGA novel
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.654
- REVEL 0.72
- MetaLR 0.79
- MetaSVM 0.69
- CADD 22.50
- PolyPhen-2 0.87
- SIFT 0.00
- UniProt: Variant assessed as somatic; moderate impact.
- Population evidence available
- Structural context available