V5M (p.Val5Met) variant of PLK1 (P53350)
V5M (p.Val5Met) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
V5M (p.Val5Met) variant details
- p.Val5Met
- gnomAD rs1290386708
- Missense
- Variant Prioritization Score for Impact Estimate 0.196
- REVEL 0.10
- CADD 17.80
- PolyPhen-2 0.08
- SIFT 0.04
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available