V43F (p.Val43Phe) variant of PLK1 (P53350)
V43F (p.Val43Phe) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data, published literature, and structural context.
V43F (p.Val43Phe) variant details
- p.Val43Phe
- gnomAD 16-23679059-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.318
- REVEL 0.31
- CADD 19.10
- PolyPhen-2 0.01
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available