V25I (p.Val25Ile) variant of PLK1 (P53350)
V25I (p.Val25Ile) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
V25I (p.Val25Ile) variant details
- p.Val25Ile
- ExAC rs749921244
- TOPMed rs749921244
- gnomAD rs749921244
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.06
- CADD 3.32
- PolyPhen-2 0.01
- SIFT 0.68
- Most common in the Latino/Admixed American population (allele frequency 6.8e-05)
- Structural context available