V22F (p.Val22Phe) variant of PLK1 (P53350)
V22F (p.Val22Phe) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
V22F (p.Val22Phe) variant details
- p.Val22Phe
- gnomAD 16-23678996-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.18
- CADD 17.10
- PolyPhen-2 0.03
- SIFT 0.19
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available