V22A (p.Val22Ala) variant of PLK1 (P53350)
V22A (p.Val22Ala) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data, published literature, and structural context.
V22A (p.Val22Ala) variant details
- p.Val22Ala
- gnomAD 16-23678997-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.146
- REVEL 0.20
- CADD 0.00
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available