T6S (p.Thr6Ser) variant of PLK1 (P53350)
T6S (p.Thr6Ser) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
T6S (p.Thr6Ser) variant details
- p.Thr6Ser
- gnomAD 16-23678949-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.194
- REVEL 0.09
- CADD 12.80
- PolyPhen-2 0.01
- SIFT 0.47
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available