T6A (p.Thr6Ala) variant of PLK1 (P53350)
T6A (p.Thr6Ala) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
T6A (p.Thr6Ala) variant details
- p.Thr6Ala
- gnomAD rs1423596323
- Missense
- Variant Prioritization Score for Impact Estimate 0.367
- REVEL 0.17
- CADD 6.74
- PolyPhen-2 0.01
- SIFT 0.83
- Most common in the Latino/Admixed American population (allele frequency 2.6e-05)
- Structural context available