S49R (p.Ser49Arg) variant of PLK1 (P53350)
S49R (p.Ser49Arg) in PLK1 (P53350) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
S49R (p.Ser49Arg) variant details
- p.Ser49Arg
- gnomAD 16-23679076-C-CAG
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.433
- CADD 29.60
- Population evidence available
- Structural context available
- Literature evidence available