S49N (p.Ser49Asn) variant of PLK1 (P53350)
S49N (p.Ser49Asn) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
S49N (p.Ser49Asn) variant details
- p.Ser49Asn
- gnomAD 16-23679078-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.25
- CADD 22.30
- PolyPhen-2 0.00
- SIFT 0.22
- Population evidence available
- Structural context available
- Literature evidence available