S2I (p.Ser2Ile) variant of PLK1 (P53350)
S2I (p.Ser2Ile) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data, published literature, and structural context.
S2I (p.Ser2Ile) variant details
- p.Ser2Ile
- gnomAD 16-23678937-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.203
- REVEL 0.13
- CADD 20.90
- PolyPhen-2 0.03
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available