R57H (p.Arg57His) variant of PLK1 (P53350)
R57H (p.Arg57His) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
R57H (p.Arg57His) variant details
- p.Arg57His
- gnomAD 16-23679102-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.20
- CADD 32.00
- PolyPhen-2 0.49
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available