R55W (p.Arg55Trp) variant of PLK1 (P53350)
R55W (p.Arg55Trp) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.67 / 1. The record also includes population frequency data and structural context.
R55W (p.Arg55Trp) variant details
- p.Arg55Trp
- Ensembl rs984792608
- Missense
- Variant Prioritization Score for Impact Estimate 0.667
- REVEL 0.67
- CADD 32.00
- PolyPhen-2 0.78
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available