R51W (p.Arg51Trp) variant of PLK1 (P53350)
R51W (p.Arg51Trp) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data, published literature, and structural context.
R51W (p.Arg51Trp) variant details
- p.Arg51Trp
- gnomAD 16-23679083-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.434
- REVEL 0.31
- CADD 32.00
- PolyPhen-2 0.88
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available