R50G (p.Arg50Gly) variant of PLK1 (P53350)
R50G (p.Arg50Gly) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
R50G (p.Arg50Gly) variant details
- p.Arg50Gly
- ExAC rs764772076
- TOPMed rs764772076
- gnomAD rs764772076
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.27
- CADD 22.40
- PolyPhen-2 0.00
- SIFT 0.90
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available