P47S (p.Pro47Ser) variant of PLK1 (P53350)
P47S (p.Pro47Ser) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data and structural context.
P47S (p.Pro47Ser) variant details
- p.Pro47Ser
- TOPMed rs1369881552
- gnomAD rs1369881552
- Missense
- Variant Prioritization Score for Impact Estimate 0.46
- REVEL 0.26
- CADD 22.70
- PolyPhen-2 0.03
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available