P41T (p.Pro41Thr) variant of PLK1 (P53350)
P41T (p.Pro41Thr) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
P41T (p.Pro41Thr) variant details
- p.Pro41Thr
- TOPMed rs1241134783
- gnomAD rs1241134783
- Missense
- Variant Prioritization Score for Impact Estimate 0.577
- REVEL 0.54
- CADD 26.60
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available