P41S (p.Pro41Ser) variant of PLK1 (P53350)
P41S (p.Pro41Ser) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
P41S (p.Pro41Ser) variant details
- p.Pro41Ser
- TOPMed rs1241134783
- gnomAD rs1241134783
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.46
- CADD 27.00
- PolyPhen-2 0.95
- SIFT 0.04
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available