P35L (p.Pro35Leu) variant of PLK1 (P53350)
P35L (p.Pro35Leu) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
P35L (p.Pro35Leu) variant details
- p.Pro35Leu
- TOPMed rs1212626444
- gnomAD rs1212626444
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.22
- CADD 15.10
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available