P28T (p.Pro28Thr) variant of PLK1 (P53350)
P28T (p.Pro28Thr) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
P28T (p.Pro28Thr) variant details
- p.Pro28Thr
- gnomAD 16-23679014-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.21
- CADD 10.00
- PolyPhen-2 0.02
- SIFT 0.07
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available