P28L (p.Pro28Leu) variant of PLK1 (P53350)
P28L (p.Pro28Leu) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.36 / 1. The record also includes population frequency data and structural context.
P28L (p.Pro28Leu) variant details
- p.Pro28Leu
- ExAC rs748043179
- TOPMed rs748043179
- gnomAD rs748043179
- Missense
- Variant Prioritization Score for Impact Estimate 0.356
- REVEL 0.29
- CADD 15.00
- PolyPhen-2 0.02
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available