P14A (p.Pro14Ala) variant of PLK1 (P53350)
P14A (p.Pro14Ala) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
P14A (p.Pro14Ala) variant details
- p.Pro14Ala
- ExAC rs764367827
- TOPMed rs764367827
- gnomAD rs764367827
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- REVEL 0.17
- CADD 19.80
- PolyPhen-2 0.01
- SIFT 0.06
- Most common in the Middle Eastern population (allele frequency 0.00064)
- Structural context available