L10M (p.Leu10Met) variant of PLK1 (P53350)
L10M (p.Leu10Met) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
L10M (p.Leu10Met) variant details
- p.Leu10Met
- gnomAD rs1278321103
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.16
- CADD 21.30
- PolyPhen-2 0.00
- SIFT 0.18
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available