K19R (p.Lys19Arg) variant of PLK1 (P53350)
K19R (p.Lys19Arg) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
K19R (p.Lys19Arg) variant details
- p.Lys19Arg
- TOPMed rs966462064
- gnomAD rs966462064
- Missense
- Variant Prioritization Score for Impact Estimate 0.224
- REVEL 0.11
- CADD 21.50
- PolyPhen-2 0.00
- SIFT 0.08
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available