K19E (p.Lys19Glu) variant of PLK1 (P53350)
K19E (p.Lys19Glu) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
K19E (p.Lys19Glu) variant details
- p.Lys19Glu
- gnomAD rs1453123013
- Missense
- Variant Prioritization Score for Impact Estimate 0.336
- REVEL 0.15
- CADD 22.60
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available