I40T (p.Ile40Thr) variant of PLK1 (P53350)
I40T (p.Ile40Thr) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
I40T (p.Ile40Thr) variant details
- p.Ile40Thr
- gnomAD 16-23679051-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.607
- REVEL 0.57
- CADD 29.00
- PolyPhen-2 0.76
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available