G8W (p.Gly8Trp) variant of PLK1 (P53350)
G8W (p.Gly8Trp) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data, published literature, and structural context.
G8W (p.Gly8Trp) variant details
- p.Gly8Trp
- gnomAD 16-23678954-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.501
- REVEL 0.32
- CADD 24.90
- PolyPhen-2 0.41
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available