G8V (p.Gly8Val) variant of PLK1 (P53350)
G8V (p.Gly8Val) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
G8V (p.Gly8Val) variant details
- p.Gly8Val
- gnomAD 16-23678955-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.27
- CADD 23.20
- PolyPhen-2 0.10
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available