G24A (p.Gly24Ala) variant of PLK1 (P53350)
G24A (p.Gly24Ala) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
G24A (p.Gly24Ala) variant details
- p.Gly24Ala
- gnomAD 16-23679003-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.13
- CADD 14.70
- PolyPhen-2 0.00
- SIFT 0.41
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available