G21W (p.Gly21Trp) variant of PLK1 (P53350)
G21W (p.Gly21Trp) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
G21W (p.Gly21Trp) variant details
- p.Gly21Trp
- gnomAD 16-23678993-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.439
- REVEL 0.36
- CADD 26.70
- PolyPhen-2 0.92
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available