G18V (p.Gly18Val) variant of PLK1 (P53350)
G18V (p.Gly18Val) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
G18V (p.Gly18Val) variant details
- p.Gly18Val
- gnomAD 16-23678985-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.20
- CADD 23.80
- PolyPhen-2 0.08
- SIFT 0.31
- Population evidence available
- Structural context available
- Literature evidence available