E42Q (p.Glu42Gln) variant of PLK1 (P53350)
E42Q (p.Glu42Gln) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data, published literature, and structural context.
E42Q (p.Glu42Gln) variant details
- p.Glu42Gln
- gnomAD 16-23679056-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.418
- REVEL 0.19
- CADD 23.40
- PolyPhen-2 0.04
- SIFT 0.18
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available