E39D (p.Glu39Asp) variant of PLK1 (P53350)
E39D (p.Glu39Asp) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
E39D (p.Glu39Asp) variant details
- p.Glu39Asp
- Ensembl rs1260213034
- Missense
- Variant Prioritization Score for Impact Estimate 0.368
- REVEL 0.26
- CADD 22.20
- PolyPhen-2 0.03
- SIFT 0.33
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)
- Structural context available