D16Y (p.Asp16Tyr) variant of PLK1 (P53350)
D16Y (p.Asp16Tyr) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
D16Y (p.Asp16Tyr) variant details
- p.Asp16Tyr
- Ensembl rs1959277217
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.26
- CADD 24.00
- PolyPhen-2 0.24
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.00021)
- Structural context available