D16G (p.Asp16Gly) variant of PLK1 (P53350)
D16G (p.Asp16Gly) in PLK1 (P53350) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
D16G (p.Asp16Gly) variant details
- p.Asp16Gly
- gnomAD 16-23678979-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.377
- REVEL 0.22
- CADD 23.70
- PolyPhen-2 0.00
- SIFT 0.36
- Most common in the Non-Finnish European population (allele frequency 9.1e-07)
- Structural context available
- Literature evidence available